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Etoposide Induces ATM-Dependent Mitochondrial Biogenesis through AMPK Activation
BACKGROUND: DNA damage such as double-stranded DNA breaks (DSBs) has been reported to stimulate mitochondrial biogenesis. However, the underlying mechanism is poorly understood. The major player in response to DSBs is ATM (ataxia telangiectasia mutated). Upon sensing DSBs, ATM is activated through a...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2329593/ https://ncbi.nlm.nih.gov/pubmed/18431490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002009 |
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