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Selective Loss of Leptin Receptors in the Ventromedial Hypothalamic Nucleus Results in Increased Adiposity and a Metabolic Syndrome

Leptin, an adipocyte-derived hormone, has emerged as a critical regulator of energy homeostasis. The leptin receptor (Lepr) is expressed in discrete regions of the brain; among the sites of highest expression are several mediobasal hypothalamic nuclei known to play a role in energy homeostasis, incl...

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Hlavní autoři: Bingham, Nathan C., Anderson, Kimberly K., Reuter, Anne L., Stallings, Nancy R., Parker, Keith L.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Endocrine Society 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2329259/
https://ncbi.nlm.nih.gov/pubmed/18258679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-1200
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