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Correlation between (13)C(α) chemical shifts and helix content of peptide ensembles

Replica exchange molecular dynamics simulations are used to generate three ensembles of an S-peptide analog (AETAAAKFLREHMDS). Percent helicity of the peptide ensembles calculated using STRIDE is compared to percent helicity calculated from (13)C(α) chemical shift deviations (CSD) from random coil i...

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Détails bibliographiques
Auteurs principaux: Weinstock, Daniel S., Narayanan, Chitra, Baum, Jean, Levy, Ronald M.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2327285/
https://ncbi.nlm.nih.gov/pubmed/18436960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.073365408
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