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Structural basis for the NAD-hydrolysis mechanism and the ARTT-loop plasticity of C3 exoenzymes
C3-like exoenzymes are ADP-ribosyltransferases that specifically modify some Rho GTPase proteins, leading to their sequestration in the cytoplasm, and thus inhibiting their regulatory activity on the actin cytoskeleton. This modification process goes through three sequential steps involving NAD-hydr...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2327275/ https://ncbi.nlm.nih.gov/pubmed/18369192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.073398508 |
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