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Production and functional analysis of rat CD59 and chimeric CD59‐Crry as active soluble proteins in Pichia pastoris

Crry (CR1‐related gene/protein) is a rodent complement regulator that inhibits C3 convertases. CD59 is a conserved protein inhibitor active towards C8 and C9. We have previously produced rat Crry as a recombinant soluble (rs) protein in Pichia pastoris. In this study we produced functionally active...

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Main Authors: Quigg, R J, He, C, Hack, B K, Alexander, J J, Morgan, B P
格式: Artigo
語言:Inglês
出版: Blackwell Science Inc 2000
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2327136/
https://ncbi.nlm.nih.gov/pubmed/10651940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2000.00945.x
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