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Dendritic cell–B-cell interaction: dendritic cells provide B cells with CD40-independent proliferation signals and CD40-dependent survival signals

Dendritic cells (DC) have recently been shown to play an important role in B-cell function. We have previously shown that DC can capture and retain unprocessed antigen in vitro and in vivo, and can transfer this antigen to naive B cells to initiate antigen-specific antibody responses. We also demons...

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Autori principali: Wykes, M, Macpherson, G
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2326988/
https://ncbi.nlm.nih.gov/pubmed/10809952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2000.00044.x
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