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Interleukin‐12 modulates T‐cell responses to microfilariae but fails to abrogate interleukin‐5‐dependent immunity in a mouse model of onchocerciasis

Infection of mice with microfilariae of Onchocerca lienalis induces high levels of protective immunity to reinfection, which is dependent on interleukin (IL)‐5 but not IL‐4. Here, we have investigated the effect of exogenous IL‐12 administration during either the priming or effector phases of the im...

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Detaylı Bibliyografya
Asıl Yazarlar: Hogarth, P J, Bianco, A E
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Science Inc 1999
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2326952/
https://ncbi.nlm.nih.gov/pubmed/10583601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.1999.00891.x
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