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Interleukin‐12 modulates T‐cell responses to microfilariae but fails to abrogate interleukin‐5‐dependent immunity in a mouse model of onchocerciasis
Infection of mice with microfilariae of Onchocerca lienalis induces high levels of protective immunity to reinfection, which is dependent on interleukin (IL)‐5 but not IL‐4. Here, we have investigated the effect of exogenous IL‐12 administration during either the priming or effector phases of the im...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
1999
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2326952/ https://ncbi.nlm.nih.gov/pubmed/10583601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.1999.00891.x |
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