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Inability of interleukin-12 to modulate T-helper 0 effectors to T-helper 1 effectors: a possible distinct subset of T cells

Interleukin-12 (IL-12) strongly favours the development of T-helper 1 (Th1)-type cells through its ability to induce interferon-γ (IFN-γ) production by natural killer cells and T cells. In the present work we analysed the effects of IL-12 on the synthesis and secretion of IFN-γ and IL-4 by human T-c...

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Bibliographic Details
Main Authors: HU, C, SALGAME, P
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 1999
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2326798/
https://ncbi.nlm.nih.gov/pubmed/10447718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.1999.00745.x
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