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Dichloroacetate modulates cytokines toward T helper 1 function via induction of the interleukin-12–interferon-γ pathway

BACKGROUND: Dichloroacetate (DCA) is one of the new, promising anticancer drugs. DCA restores normal mitochondrial function and enables cancer cells to undergo apoptosis. In addition, DCA was found to modulate certain signaling pathways involving some transcription factors. The latter encouraged us...

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Detalhes bibliográficos
Main Authors: Badr, Mujtaba M, Qinna, Nidal A, Qadan, Fadi, Matalka, Khalid Z
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923616/
https://ncbi.nlm.nih.gov/pubmed/24532971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S56688
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