Dichloroacetate modulates cytokines toward T helper 1 function via induction of the interleukin-12–interferon-γ pathway

BACKGROUND: Dichloroacetate (DCA) is one of the new, promising anticancer drugs. DCA restores normal mitochondrial function and enables cancer cells to undergo apoptosis. In addition, DCA was found to modulate certain signaling pathways involving some transcription factors. The latter encouraged us...

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Autori principali: Badr, Mujtaba M, Qinna, Nidal A, Qadan, Fadi, Matalka, Khalid Z
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2014
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923616/
https://ncbi.nlm.nih.gov/pubmed/24532971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S56688
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