Overexpression of interleukin-12 and T helper 1 predominance in lupus nephritis

Imbalance of cytokine homeostasis is a prominent feature of both experimental and human systemic lupus erythematosus (SLE). Because interleukin (IL)-12 promotes interferon (IFN)-γ production leading to polarization of peripheral cells toward a T helper (Th) 1 phenotype, we investigated its role in l...

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Bibliographic Details
Main Authors: Tucci, M, Lombardi, L, Richards, H B, Dammacco, F, Silvestris, F
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2008
Subjects:
Animal Studies
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612719/
https://ncbi.nlm.nih.gov/pubmed/18795942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2008.03758.x
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