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Effect of CD8(+) T-cell depletion on bronchial hyper-responsiveness and inflammation in sensitized and allergen-exposed Brown–Norway rats
We examined the role of CD8(+) T cells in a Brown–Norway rat model of asthma, using a monoclonal antibody to deplete CD8(+) T cells. Ovalbumin (OA)-sensitized animals were given anti-CD8 antibody (0·5 mg/rat) intravenously 1 week prior to exposure to 1% OA aerosol and were studied 18–24 hr after aer...
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| Asıl Yazarlar: | , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Blackwell Science Inc
1999
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2326765/ https://ncbi.nlm.nih.gov/pubmed/10233723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.1999.00699.x |
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