Adoptive transfer of allergen-specific CD4+ T cells induces airway inflammation and hyperresponsiveness in brown-Norway rats.

Following allergen exposure, sensitized Brown-Norway rats develop airway hyperresponsiveness (AHR) and eosinophilic inflammation together with an increase in activated T cells (CD25+) in the airways. We tested the hypothesis that CD4+ T cells are involved directly in the acquisition of AHR. Spleen T...

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Autori principali: Haczku, A, Macary, P, Huang, T J, Tsukagoshi, H, Barnes, P J, Kay, A B, Kemeny, D M, Chung, K F, Moqbel, R
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1997
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1363844/
https://ncbi.nlm.nih.gov/pubmed/9227314
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