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Mechanism of airway hyperresponsiveness to adenosine induced by allergen challenge in actively sensitized Brown Norway rats

1. We have explored the role of allergen sensitization and challenge in defining the response of the airways of the Brown Norway (BN) rat to adenosine. 2. In naïve animals or in rats sensitized to ovalbumin (OA) adenosine induced only weak bronchoconstrictor responses. Challenge of sensitized animal...

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Detalhes bibliográficos
Main Authors: Hannon, J P, Tigani, B, Williams, I, Mazzoni, L, Fozard, J R
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572696/
https://ncbi.nlm.nih.gov/pubmed/11264245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703961
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