Surface-expressed invariant chain (CD74) is required for internalization of human leucocyte antigen-DR molecules to early endosomal compartments

Transport of major histocompatibility complex (MHC) class II molecules to the endocytic route is directed by the associated invariant chain (Ii). In the endocytic pathway, Ii is proteolytically cleaved and, upon removal of residual Ii fragments, class II αβ dimers are charged with antigenic peptide...

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Autores principales: Moldenhauer, G, Henne, C, Karhausen, J, Möller, P
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 1999
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2326754/
https://ncbi.nlm.nih.gov/pubmed/10233730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.1999.00676.x
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