Cargando...

Surface-expressed invariant chain (CD74) is required for internalization of human leucocyte antigen-DR molecules to early endosomal compartments

Transport of major histocompatibility complex (MHC) class II molecules to the endocytic route is directed by the associated invariant chain (Ii). In the endocytic pathway, Ii is proteolytically cleaved and, upon removal of residual Ii fragments, class II αβ dimers are charged with antigenic peptide...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Moldenhauer, G, Henne, C, Karhausen, J, Möller, P
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 1999
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2326754/
https://ncbi.nlm.nih.gov/pubmed/10233730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.1999.00676.x
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!