The activity of the high-affinity K+ uptake system Kdp sensitizes cells of Escherichia coli to methylglyoxal.

Expression of the Kdp system sensitizes cells to methylglyoxal (MG) whether this electrophile is added externally or is synthesized endogenously. The basis of this enhanced sensitivity is the maintenance of a higher cytoplasmic pH (pHi) in cells expressing Kdp. In such cells, MG elicits rapid cytopl...

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Бібліографічні деталі

Опубліковано в::	J Bacteriol
Автори:	Ferguson, G P, Chacko, A D, Lee, C H, Booth, I R, Lee, C
Формат:	Artigo
Мова:	Inglês
Опубліковано:	American Society for Microbiology (ASM) 1996
Предмети:	Research Article
Онлайн доступ:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232660/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8682804/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.178.13.3957-3961.1996
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