The activity of the high-affinity K+ uptake system Kdp sensitizes cells of Escherichia coli to methylglyoxal.

Expression of the Kdp system sensitizes cells to methylglyoxal (MG) whether this electrophile is added externally or is synthesized endogenously. The basis of this enhanced sensitivity is the maintenance of a higher cytoplasmic pH (pHi) in cells expressing Kdp. In such cells, MG elicits rapid cytopl...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Ferguson, G P, Chacko, A D, Lee, C H, Booth, I R, Lee, C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232660/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8682804/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.178.13.3957-3961.1996
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