The activity of the high-affinity K+ uptake system Kdp sensitizes cells of Escherichia coli to methylglyoxal.

Expression of the Kdp system sensitizes cells to methylglyoxal (MG) whether this electrophile is added externally or is synthesized endogenously. The basis of this enhanced sensitivity is the maintenance of a higher cytoplasmic pH (pHi) in cells expressing Kdp. In such cells, MG elicits rapid cytopl...

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Detalles Bibliográficos

Publicado en:	J Bacteriol
Autores principales:	Ferguson, G P, Chacko, A D, Lee, C H, Booth, I R, Lee, C
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1996
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232660/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8682804/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.178.13.3957-3961.1996
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