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Changes of telomere length cause reciprocal changes in the lifespan of mother cells in Saccharomyces cerevisiae

Budding yeast cells divide asymmetrically, giving rise to a mother and its daughter. Mother cells have a limited division potential, called their lifespan, which ends in proliferation-arrest and lysis. In this report we mutate telomerase in Saccharomyces cerevisiae to shorten telomeres and show that...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Austriaco, Nicanor R., Guarente, Leonard P.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1997
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On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23265/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9275199/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.18.9768
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