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Changes of telomere length cause reciprocal changes in the lifespan of mother cells in Saccharomyces cerevisiae

Budding yeast cells divide asymmetrically, giving rise to a mother and its daughter. Mother cells have a limited division potential, called their lifespan, which ends in proliferation-arrest and lysis. In this report we mutate telomerase in Saccharomyces cerevisiae to shorten telomeres and show that...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
I whakaputaina i:Proc Natl Acad Sci U S A
Ngā kaituhi matua: Austriaco, Nicanor R., Guarente, Leonard P.
Hōputu: Artigo
Reo:Inglês
I whakaputaina: National Academy of Sciences 1997
Ngā marau:
Urunga tuihono:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23265/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9275199/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.18.9768
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