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UV-induced mutagenesis of human p53 in a vector replicated in Saccharomyces cerevisiae

Mutation of the p53 tumor suppressor gene is the most common genetic alteration identified to date in human cancers. Similarities of p53 mutations found in human cancers with those induced in experimental systems have been interpreted as evidence supporting a causative role for environmental carcino...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Moshinsky, Deborah J., Wogan, Gerald N.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20076/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9122183/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.6.2266
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