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UV-induced mutagenesis of human p53 in a vector replicated in Saccharomyces cerevisiae

Mutation of the p53 tumor suppressor gene is the most common genetic alteration identified to date in human cancers. Similarities of p53 mutations found in human cancers with those induced in experimental systems have been interpreted as evidence supporting a causative role for environmental carcino...

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Detalhes bibliográficos
Main Authors: Moshinsky, Deborah J., Wogan, Gerald N.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC20076/
https://ncbi.nlm.nih.gov/pubmed/9122183
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