UV-induced mutagenesis of human p53 in a vector replicated in Saccharomyces cerevisiae
Mutation of the p53 tumor suppressor gene is the most common genetic alteration identified to date in human cancers. Similarities of p53 mutations found in human cancers with those induced in experimental systems have been interpreted as evidence supporting a causative role for environmental carcino...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1997
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20076/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9122183/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.6.2266 |
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