Mutations of N-terminal regions render the retinoblastoma protein insufficient for functions in development and tumor suppression.
To assess biological roles of the retinoblastoma protein (RB), four independent transgenic mouse lines expressing human RB with different deletions in the N-terminal region (RBdeltaN) were generated and compared with mice expressing identically regulated, full-length RB. Expression of both RB and RB...
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| Publicado en: | Mol Cell Biol |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Taylor & Francis
1997
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232590/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9372965/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.12.7342 |
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