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Tumor Suppression by a Severely Truncated Species of Retinoblastoma Protein
Rb(+/+):Rb(−/−) chimeric mice are healthy until early in adulthood when they develop lethal pituitary tumors composed solely of Rb(−/−) cells. In an effort to delineate the minimal structures of the retinoblastoma protein necessary for RB tumor suppression function, chimeric animals derived from sta...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC133747/ https://ncbi.nlm.nih.gov/pubmed/11940667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.9.3103-3110.2002 |
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