Tumor Suppression by a Severely Truncated Species of Retinoblastoma Protein

Rb(+/+):Rb(−/−) chimeric mice are healthy until early in adulthood when they develop lethal pituitary tumors composed solely of Rb(−/−) cells. In an effort to delineate the minimal structures of the retinoblastoma protein necessary for RB tumor suppression function, chimeric animals derived from sta...

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Main Authors: Yang, Hong, Williams, Bart O., Hinds, Phillip W., Shih, T. Shane, Jacks, Tyler, Bronson, Roderick T., Livingston, David M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2002
Ábhair:
Cell Growth and Development
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC133747/
https://ncbi.nlm.nih.gov/pubmed/11940667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.9.3103-3110.2002
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