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Hepatocyte nuclear factor 3beta is involved in pancreatic beta-cell-specific transcription of the pdx-1 gene.

The mammalian homeobox gene pdx-1 is expressed in pluripotent precursor cells in the dorsal and ventral pancreatic bud and duodenal endoderm, which will produce the pancreas and the rostral duodenum. In the adult, pdr-1 is expressed principally within insulin-secreting pancreatic islet beta cells an...

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Autors principals: Wu, K L, Gannon, M, Peshavaria, M, Offield, M F, Henderson, E, Ray, M, Marks, A, Gamer, L W, Wright, C V, Stein, R
Format: Artigo
Idioma:Inglês
Publicat: 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC232449/
https://ncbi.nlm.nih.gov/pubmed/9315659
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