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FKBP12 physically and functionally interacts with aspartokinase in Saccharomyces cerevisiae.
The peptidyl-prolyl isomerase FKBP12 was originally identified as the intracellular receptor for the immunosuppressive drugs FK506 (tacrolimus) and rapamycin (sirolimus). Although peptidyl-prolyl isomerases have been implicated in catalyzing protein folding, the cellular functions of FKBP12 in Sacch...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1997
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC232445/ https://ncbi.nlm.nih.gov/pubmed/9315655 |
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