Functions of FKBP12 and Mitochondrial Cyclophilin Active Site Residues In Vitro and In Vivo in Saccharomyces cerevisiae

Cyclophilin and FK506 binding protein (FKBP) accelerate cis–trans peptidyl-prolyl isomerization and bind to and mediate the effects of the immunosuppressants cyclosporin A and FK506. The normal cellular functions of these proteins, however, are unknown. We altered the active sites of FKBP12 and mito...

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Publicado en:	Mol Biol Cell
Autores principales:	Dolinski, Kara, Scholz, Christian, Muir, R. Scott, Rospert, Sabine, Schmid, Franz X., Cardenas, Maria E., Heitman, Joseph
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Cell Biology 1997
Materias:	Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25707/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9362068/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.8.11.2267
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