Complementary DNA encoding the human T-cell FK506-binding protein, a peptidylprolyl cis-trans isomerase distinct from cyclophilin.

The recently discovered macrolide FK506 has been demonstrated to have potent immunosuppressive activity at concentrations 100-fold lower than cyclosporin A, a cyclic undecapeptide that is used to prevent rejection after transplantation of bone marrow and organs, such as kidney, heart, and liver. Aft...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Maki, N, Sekiguchi, F, Nishimaki, J, Miwa, K, Hayano, T, Takahashi, N, Suzuki, M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54340/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1695378/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.14.5440
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