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FKBP12 Controls Aspartate Pathway Flux in Saccharomyces cerevisiae To Prevent Toxic Intermediate Accumulation

FKBP12 is a conserved member of the prolyl-isomerase enzyme family and serves as the intracellular receptor for FK506 that mediates immunosuppression in mammals and antimicrobial actions in fungi. To investigate the cellular functions of FKBP12 in Saccharomyces cerevisiae, we employed a high-through...

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Detalhes bibliográficos
Main Authors: Arévalo-Rodríguez, Miguel, Pan, Xuewen, Boeke, Jef D., Heitman, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC522611/
https://ncbi.nlm.nih.gov/pubmed/15470257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.3.5.1287-1296.2004
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