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High Distribution of CD40 and TRAF2 in Th40 T Cell Rafts Leads to Preferential Survival of this Auto-Aggressive Population in Autoimmunity

BACKGROUND: CD40–CD154 interactions have proven critical in autoimmunity, with the identification of CD4(lo)CD40(+) T cells (Th40 cells) as harboring an autoaggressive T cell population shedding new insights into those disease processes. Th40 cells are present at contained levels in non-autoimmune i...

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Autori principali: Vaitaitis, Gisela M., Wagner, David H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2324204/
https://ncbi.nlm.nih.gov/pubmed/18446238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002076
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