Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1.

The Raf family of protein kinases display differences in their abilities to promote the entry of quiescent NIH 3T3 cells into the S phase of the cell cycle. Although conditional activation of deltaA-Raf:ER promoted cell cycle progression, activation of deltaRaf-1:ER and deltaB-Raf:ER elicited a G1 a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Woods, D, Parry, D, Cherwinski, H, Bosch, E, Lees, E, McMahon, M
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1997
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC232408/
https://ncbi.nlm.nih.gov/pubmed/9271435
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