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Mutations in the conserved C-terminal sequence in thyroid hormone receptor dissociate hormone-dependent activation from interference with AP-1 activity.

A short C-terminal sequence that is deleted in the v-ErbA oncoprotein and conserved in members of the nuclear receptor superfamily is required for normal biological function of its normal cellular counterpart, the thyroid hormone receptor alpha (T3R alpha). We carried out an extensive mutational ana...

詳細記述

保存先:
書誌詳細
主要な著者: Saatcioglu, F, Lopez, G, West, B L, Zandi, E, Feng, W, Lu, H, Esmaili, A, Apriletti, J W, Kushner, P J, Baxter, J D, Karin, M
フォーマット: Artigo
言語:Inglês
出版事項: 1997
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC232321/
https://ncbi.nlm.nih.gov/pubmed/9234725
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