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Positive and negative modulation of Jun action by thyroid hormone receptor at a unique AP1 site.

We have characterized the putative AP1 site in the backbone of pUC plasmids and found unique regulatory effects. The site, which mapped to a 19-bp region around nucleotide 37, conferred transcriptional activation by Jun or Jun/Fos that was boosted up to fivefold by unliganded thyroid hormone recepto...

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Publicado en:Mol Cell Biol
Autores principales: Lopez, G, Schaufele, F, Webb, P, Holloway, J M, Baxter, J D, Kushner, P J
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 1993
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359696/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8474460/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.5.3042-3049.1993
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