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Positive and negative modulation of Jun action by thyroid hormone receptor at a unique AP1 site.

We have characterized the putative AP1 site in the backbone of pUC plasmids and found unique regulatory effects. The site, which mapped to a 19-bp region around nucleotide 37, conferred transcriptional activation by Jun or Jun/Fos that was boosted up to fivefold by unliganded thyroid hormone recepto...

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Détails bibliographiques
Auteurs principaux: Lopez, G, Schaufele, F, Webb, P, Holloway, J M, Baxter, J D, Kushner, P J
Format: Artigo
Langue:Inglês
Publié: 1993
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC359696/
https://ncbi.nlm.nih.gov/pubmed/8474460
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