Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation.

Cell attachment to fibronectin stimulates the integrin-dependent interaction of p85-associated phosphatidylinositol (PI) 3-kinase with integrin-dependent focal adhesion kinase (FAK) as well as activation of the Ras/mitogen-activated protein (MAP) kinase pathway. However, it is not known if this PI 3...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	King, W G, Mattaliano, M D, Chan, T O, Tsichlis, P N, Brugge, J S
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1997
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232295/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9234699/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.8.4406
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