Fe-catalyzed cleavage of the α subunit of Na/K-ATPase: Evidence for conformation-sensitive interactions between cytoplasmic domains

Incubation of Na/K-ATPase with ascorbate plus H(2)O(2) produces specific cleavage of the α subunit. Five fragments with intact C termini and complementary fragments with intact N termini were observed. The β subunit is not cleaved. Cleavages depend on the presence of contaminant or added Fe(2+) ions...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Goldshleger, Rivka, Karlish, Steven J. D.
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1997
Fag:	Biological Sciences
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23229/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9275168/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.18.9596
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