Fe-catalyzed cleavage of the α subunit of Na/K-ATPase: Evidence for conformation-sensitive interactions between cytoplasmic domains
Incubation of Na/K-ATPase with ascorbate plus H(2)O(2) produces specific cleavage of the α subunit. Five fragments with intact C termini and complementary fragments with intact N termini were observed. The β subunit is not cleaved. Cleavages depend on the presence of contaminant or added Fe(2+) ions...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1997
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23229/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9275168/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.18.9596 |
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