Fe-catalyzed cleavage of the α subunit of Na/K-ATPase: Evidence for conformation-sensitive interactions between cytoplasmic domains

Incubation of Na/K-ATPase with ascorbate plus H(2)O(2) produces specific cleavage of the α subunit. Five fragments with intact C termini and complementary fragments with intact N termini were observed. The β subunit is not cleaved. Cleavages depend on the presence of contaminant or added Fe(2+) ions...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Goldshleger, Rivka, Karlish, Steven J. D.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1997
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23229/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9275168/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.18.9596
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!