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Efficient repression of endogenous major histocompatibility complex class II expression through dominant negative CIITA mutants isolated by a functional selection strategy.

Major histocompatibility complex class II (MHC-II) molecules present peptide antigens to CD4-positive T cells and are of critical importance for the immune response. The MHC-II transactivator CIITA is essential for all aspects of MHC-II gene expression examined so far and thus constitutes a master r...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
-д хэвлэсэн:Mol Cell Biol
Үндсэн зохиолчид: Bontron, S, Ucla, C, Mach, B, Steimle, V
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Taylor & Francis 1997
Нөхцлүүд:
Онлайн хандалт:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232278/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9234682/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.8.4249
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