Efficient repression of endogenous major histocompatibility complex class II expression through dominant negative CIITA mutants isolated by a functional selection strategy.

Major histocompatibility complex class II (MHC-II) molecules present peptide antigens to CD4-positive T cells and are of critical importance for the immune response. The MHC-II transactivator CIITA is essential for all aspects of MHC-II gene expression examined so far and thus constitutes a master r...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Bontron, S, Ucla, C, Mach, B, Steimle, V
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232278/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9234682/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.8.4249
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