Mechanism of repression of RNA polymerase I transcription by the retinoblastoma protein.

The retinoblastoma susceptibility gene product pRb restricts cellular proliferation by affecting gene expression by all three classes of nuclear RNA polymerases. To elucidate the molecular mechanisms underlying pRb-mediated repression of ribosomal DNA (rDNA) transcription by RNA polymerase I, we hav...

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Bibliographic Details
Main Authors: Voit, R, Schäfer, K, Grummt, I
Format: Artigo
Language:Inglês
Published: 1997
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC232276/
https://ncbi.nlm.nih.gov/pubmed/9234680
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