A novel transcript encoding an N-terminally truncated AML1/PEBP2 alphaB protein interferes with transactivation and blocks granulocytic differentiation of 32Dcl3 myeloid cells.

The gene AML1/PEBP2 alphaB encodes the alpha subunit of transcription factor PEBP2/CBF and is essential for the establishment of fetal liver hematopoiesis. Rearrangements of AML1 are frequently associated with several types of human leukemia. Three types of AML1 cDNA isoforms have been described to...

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Bibliografiska uppgifter
Huvudupphovsmän: Zhang, Y W, Bae, S C, Huang, G, Fu, Y X, Lu, J, Ahn, M Y, Kanno, Y, Kanno, T, Ito, Y
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1997
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC232267/
https://ncbi.nlm.nih.gov/pubmed/9199349
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