A novel transcript encoding an N-terminally truncated AML1/PEBP2 alphaB protein interferes with transactivation and blocks granulocytic differentiation of 32Dcl3 myeloid cells.

Lignende værker

• Negative regulation of granulocytic differentiation in the myeloid precursor cell line 32Dcl3 by ear-2, a mammalian homolog of Drosophila seven-up, and a chimeric leukemogenic gene, AML1/ETO(MTG8)
  af: Ahn, Mee-Young, et al.
  Udgivet: (1998)
• PEBP2 alpha B/mouse AML1 consists of multiple isoforms that possess differential transactivation potentials.
  af: Bae, S C, et al.
  Udgivet: (1994)
• Cytoplasmic Sequestration of the Polyomavirus Enhancer Binding Protein 2 (PEBP2)/Core Binding Factor α (CBFα) Subunit by the Leukemia-Related PEBP2/CBFβ-SMMHC Fusion Protein Inhibits PEBP2/CBF-Mediated Transactivation
  af: Kanno, Yuka, et al.
  Udgivet: (1998)
• The PEBP2βMYH11 fusion created by Inv(16)(p13;q22) in myeloid leukemia impairs neutrophil maturation and contributes to granulocytic dysplasia
  af: Kogan, Scott C., et al.
  Udgivet: (1998)
• PEBP2/CBF, the murine homolog of the human myeloid AML1 and PEBP2 beta/CBF beta proto-oncoproteins, regulates the murine myeloperoxidase and neutrophil elastase genes in immature myeloid cells.
  af: Nuchprayoon, I, et al.
  Udgivet: (1994)