Beta interferon and oncostatin M activate Raf-1 and mitogen-activated protein kinase through a JAK1-dependent pathway.
Activation of early response genes by interferons (IFNs) and other cytokines requires tyrosine phosphorylation of a family of transcription factors termed signal transducers and activators of transcription (Stats). The Janus family of tyrosine kinases (Jak1, Jak2, Jak3, and Tyk2) is required for cyt...
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| Udgivet i: | Mol Cell Biol |
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| Principais autores: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
1997
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232235/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9199317/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.7.3833 |
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