Beta interferon and oncostatin M activate Raf-1 and mitogen-activated protein kinase through a JAK1-dependent pathway.

Activation of early response genes by interferons (IFNs) and other cytokines requires tyrosine phosphorylation of a family of transcription factors termed signal transducers and activators of transcription (Stats). The Janus family of tyrosine kinases (Jak1, Jak2, Jak3, and Tyk2) is required for cyt...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Stancato, L F, Sakatsume, M, David, M, Dent, P, Dong, F, Petricoin, E F, Krolewski, J J, Silvennoinen, O, Saharinen, P, Pierce, J, Marshall, C J, Sturgill, T, Finbloom, D S, Larner, A C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232235/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9199317/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.7.3833
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