Beta interferon and oncostatin M activate Raf-1 and mitogen-activated protein kinase through a JAK1-dependent pathway.

Activation of early response genes by interferons (IFNs) and other cytokines requires tyrosine phosphorylation of a family of transcription factors termed signal transducers and activators of transcription (Stats). The Janus family of tyrosine kinases (Jak1, Jak2, Jak3, and Tyk2) is required for cyt...

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Main Authors: Stancato, L F, Sakatsume, M, David, M, Dent, P, Dong, F, Petricoin, E F, Krolewski, J J, Silvennoinen, O, Saharinen, P, Pierce, J, Marshall, C J, Sturgill, T, Finbloom, D S, Larner, A C
格式: Artigo
語言:Inglês
出版: 1997
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC232235/
https://ncbi.nlm.nih.gov/pubmed/9199317
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