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Cdc42 regulates anchorage-independent growth and is necessary for Ras transformation.

The Rho family members Cdc42, Rac, and Rho play a central role in the organization of the actin cytoskeleton and regulate transcription. Whereas Rac and Rho have been implicated in transformation by oncogenic Ras, the role of Cdc42 in this process remains unknown. In this study, we found that Rat1 f...

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Pubblicato in:Mol Cell Biol
Autori principali: Qiu, R G, Abo, A, McCormick, F, Symons, M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 1997
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232198/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9154844/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.6.3449
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