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Instability of CAG and CTG trinucleotide repeats in Saccharomyces cerevisiae.

A quantitative genetic assay was developed to monitor alterations in tract lengths of trinucleotide repeat sequences in Saccharomyces cerevisiae. Insertion of (CAG)50 or (CTG)50 repeats into a promoter that drives expression of the reporter gene ADE8 results in loss of expression and white colony co...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Miret, J J, Pessoa-Brandão, L, Lahue, R S
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1997
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232191/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9154837/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.6.3382
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